(This is my first post to the board)
I've been working on my daily carry system yet again and, with ideas from your posts, have put together one similiar to what Duus talks about. I did not find the Purseket too girly, so I ordered one in medium and use it inside of a Timbuk2 medium classic messenger during the day. I teach high school chemistry in SC and have three children (9,7,3), oldest two on different sports teams simultaneously, and start grad school next week in an accelerated program. I carry the Timbuk2 daily with variety of necessities and with the minimum carry in the Purseket, ready for quick transfer to the empty purse I carry in my van plus whatever else I need for that particular event.

Here's the list:
T2 bag (purple and gold)
book/mag currently reading
InBox file folder
accordion folder that holds papers to be graded
landscape homemade binder for grades/lesson plans/pacing guides
markers/pens/pencils in separate zipper pouch
beauty bag
4x6 spiral bound tickler
planner
project files in cover slips
assorted office supplies in interior pockets
school keys
mp3 & earbuds
journal
name book for collecting interesting names and personality details
memory stick
extra glasses and meds in interior pockets
Purseket with bare minimum:
moleskine pocket for daily stuff
hpda for NA's while out (@calls and @errands)
wallet
phone
car/house keys
lip stuff

And there's still room for a notebook and book for class when it starts next week. Amazing how much stuff fits in there!